GSTM1 and Pancytopenia: Among the enrolled subjects, three cases (15%) of hematological toxicity were registered, one (5%) of whom was a grade 2 Hb toxicity not needing transfusion, since it spontaneously regressed after 223Ra-therapy discontinuation; the remaining two cases (10%) presented, respectively, grade 3 Hb toxicity and pancytopenia (grade 3 Hb and PLT toxicity and grade 2 lymphocyte toxicity) and were treated with transfusions.