SIX3 and lung carcinoma: To further study the regulation of the SIX3/β-catenin axis in lung cancer pathogenesis, we performed bioinformatic analysis using UbiBrowser (http://ubibrowser.ncpsb.org/), and found based on confidence level no high-confidence interactions (defined as P < 0.001), 10 middle-confidence interactions (0.001 ≤ P < 0.01), and 67 low-confidence interactions (0.01 ≤ P < 0.05).