TARDBP and amyotrophic lateral sclerosis: To determine the diagnostic potential of TDP‐43 misfolding for differentiation of ALS versus PD and ALS versus Ctrl, we performed a ROC analysis on amide I maximum data resulting in an AUC of 0.85 (95%‐CL 0.75–0.95) for ALS versus PD and an AUC of 0.93 (95%‐CL 0.87–0.99) for ALS versus Ctrl.