To explore the effect of Kcnh2 on septic heart and cardiomyocytes, we detected the expression level of Kcnh2 in SICD, we applied CLP surgery to prepare a rat model with polymicrobial sepsis or induced endotoxaemia by intraperitoneal injection of bacterial LPS, which resulted in a typical feature of sepsis‐lung injury (Figure S2). The gene discussed is KCNH2; the disease is Sepsis.