Using published pQTL and stroke association data, colocalization analysis showed no evidence for a role of the TWEAK locus (posterior probability of a model with 1 shared common variant [PP4]: 0.006) or HGF locus (PP4: 0.005) in ischemic stroke (eFigure 11 and eMethods in the Supplement). The gene discussed is TNFSF12; the disease is ischemic stroke.