ACE2 and chronic obstructive pulmonary disease: A higher prevalence of such complications has also been reported in patients with comorbidities, such as systemic hypertension, coronary artery disease, diabetes mellitus, obesity, chronic obstructive lung disease (COPD), and asthma.(5-9) The membrane-bound angiotensin-converting-enzyme 2 functions as a receptor for SARS-CoV-2, which partially explains some of these risk factors.(10) However, the related epidemiology, clinical course, pathogenesis, and risk factors for complications of COVID-19 are not yet completely understood.