The clinical characteristics were compared between septic survivors and non-survivors, which showed that non-survivors had significantly more female cases, less cases with primary infection site, more cases with anaerobes, higher Scr, WBC, CRP, APACHE II score, and SOFA score (all P<0.05) compared with survivors, while no difference was found in age, BMI, smoking, COPD, cardiomyopathy, chronic kidney failure, cirrhosis, gram-negative bacteria, gram-positive bacteria, fungus, mycoplasmas, total negative culture, or albumin (all P>0.05) between non-survivors and survivors (Table 1). This evidence concerns the gene CRP and chronic obstructive pulmonary disease.