KLK3 and posterior cortical atrophy: The calibration plots of predicated risk against observed PCa and CSPCa risk indicated excellent concordance in multivariable models (SSR=0.033 for PCa, and SSR=0.025 for CSPCa), followed by PSA derivatives (SSR=0.130 for PCa, and SSR=0.086 for CSPCa) and mpMRI derivatives (SSR=0.190 for PCa, and SSR=0.083 for CSPCa) (Figure 3).