The results were as follows: distant metastasis (HR, 2.68), metabolic tumor volume (MTV, HR, 2.02), maximal standard uptake value (SUVmax, HR, 2.48), stage (HR, 4.29), and carcinoembryonic antigen (CEA, HR, 3.16) were the significant risk factors for patients with an EGFR mutation (P < 0.05).The significant risk factors with p < 0.05 were calculated using a log-rank test, and Kaplan–Meier curves were plotted. Here, CEACAM5 is linked to neoplasm.