CD8A and neoplasm: CD8+ T cells from splenocytes of ICT responders produced IFNγ and upregulated CD137 when co-cultured with AB1-HA tumor cells (P = 0.002) and HA peptide (P = 0.007), but minimally with AB1 or MHC-I matched control (RENCA) tumor cells (Figures 5C–E).