BDNF and cholesteryl ester measurement: In our study, we chose three representative single nucleotide polymorphisms (SNPs) of ADORA2A, BDNF, and NTRK2 genes(Supplementary Table S1) to investigate the association of their genetic polymorphism with the risk of childhood epilepsy (CE) and predisposition of this disease to comorbid neurologic and developmental disorders in Chinese southern children.