PRL and Zika virus infectious disease: In order to study ER morphology following ZIKV infection, we generated stable U87 glioblastoma cells transfected with either ER monomeric oxidizing environment-optimized green fluorescent protein (ERmoxGFP), a lumenal ER reporter containing the bovine prolactin signal sequence and KDEL ER retention sequence linked to inert, monomeric, cysteine-less moxGFP29, or the membrane-associated ER reporter Sec61β-GFP.