In this study, we used Tmem119 and P2RY12 along with a conventional combination of CD45, CD11b, and Ly6C myeloid markers in models of stroke, CAA, and aging to determine whether Tmem119+P2RY12+ cells appear within the CD45highCD11b+ gate, often referred to as the “infiltrating myeloid” gate. The gene discussed is ITGAM; the disease is stroke disorder.