Briefly, considering that the peptide with the PLGLAG is sensitive to MMP-2, abundantly present in tumor tissue, CXB was conjugated to the GGPLGLAGG peptide, and the triblock copolymer [PPLG-g-(CXB-peptide & mPEG)]-PEG-PCL (PCxbP) was manufactured through a click reaction with a prepolymer [173,174]. The gene discussed is MMP2; the disease is neoplasm.