Notably, none of the C. coli-infected TLR4−/− IL-10−/− mice and only 18.8% of the IL-10−/− counterparts were suffering from acute campylobacteriosis (as indicated by clinical scores of at ≥10), whereas 81.8% and 56.3% of infected TLR4−/− IL-10−/− and IL-10−/− mice remained clinically unaffected, respectively (Supplementary Figure S1C,D). The gene discussed is IL10; the disease is campylobacteriosis.