According to the current WHO classification, MCL diagnosis is based on its distinctive morphology and the presence of the characteristic chromosomal translocation t(11;14) (q13;q32) that juxtaposes the CCND1 gene to the immunoglobulin heavy chain (IGH) gene, thus resulting in constitutive overexpression of CyclinD1 [9]. The gene discussed is CCND1; the disease is mantle cell lymphoma.