Low β-cell function (OR = 3.046; 95% CI: 1.609, 5.766; p = 0.001) and high serum RAGE concentration (OR = 2.870; 95% CI: 1.498, 5.496; p = 0.001) were linked to diabetes, compared to non-diabetes, with three times higher likelihood. Here, AGER is linked to diabetes mellitus.