GBA2 and Gait ataxia: The patients with GBA2 mutations have progressive diseases that can present from early childhood to early adulthood and have a wide range of neurological and non-neurological symptoms, including cataracts, hypotonia, brisk tendon reflexes, gait ataxia, spasticity, and mental impairment, with thinning of the corpus callosum and atrophy of the cerebellum.