For example, specific CT scan imaging features have been associated with the presence of tumor driving mutations in lung cancer, including anaplastic lymphoma kinase (ALK), epidermal growth factor receptor (EGFR), Kirsten rat sarcoma viral oncogene homolog (KRAS), rearranged during transfection proto-oncogene (RET) and c-ros oncogene 1 (ROS1) [103,104,105]. The gene discussed is ROS1; the disease is lung cancer.