The premutation FMR1 RNA is also RAN-translated into polyA and polyglycine (polyG) peptides, which originate ubiquitin-positive intranuclear inclusions colocalizing with p62 that could also contribute to neurodegeneration in Drosophila and FXTAS brain tissue [126,127,128]. The gene discussed is FMR1; the disease is fragile X-associated tremor/ataxia syndrome.