MBNL1 and neuroblastoma: Notably, the (CUG)expATXN2-AS transcript leads to cell death of primary mouse cortical neurons and forms RNA foci in SCA2 human cerebella and BAC-transgenic mice, which likely colocalize with Muscleblind-Like Splicing Regulator 1 (MBNL1), as detected in neuroblastoma cells transfected with the expanded (CAG)n [10].