CNRIP1 and neuroblastoma: As reviewed herein, our understanding of how CRIP1a influences biochemical and cellular homeostasis has been advanced by experimentation using model cell systems, such as N18TG2 neuroblastoma cell clones expressing endogenous CRIP1a at wild-type, overexpression, or knockdown levels, and HEK293 fibroblast cells expressing exogenous CRIP1a at various levels.