In vitro studies demonstrated that 20(R),24(R)-ocotillol might ameliorate colitis by inhibiting the expression of the proinflammatory cytokines TNF-α, interleukin-1β, IL-6, interleukin-17 (IL-17), interleukin-23 (IL-23) and interferon-γ (IFN-γ). This evidence concerns the gene IL37 and colitis.