SERPINE1 and coronary artery disorder: The −675 4G > 5G polymorphism (rs1799762), located in the PAI-1 promotor region, is also reported to be associated with various atherosclerotic diseases including venous thromboembolism [20], ischemic stroke [21], carotid artery stenosis [22], renal artery stenosis [23], and coronary artery disease [24].