SNPs in pro- and anti-inflammatory adipokine genes encoding leptin, leptin receptor, adiponectin and omentin were addressed in psoriasis; however, (with the exception of one study of the rs7799039 polymorphism in the leptin gene), researchers found no correlation or increased risk of psoriasis vulgaris with these polymorphisms [85,164,169,170,171]. This evidence concerns the gene LEP and psoriasis vulgaris.