Several genes associated with proliferation and inflammatory cytokine signaling were up-regulated in RA pDCs (IFNAR1, IL6R, CSF1R, MAPK14, IL6ST) and RA CD1c+ DCs (BCL3, TNFα, CCR6, ICOSLG, BTLA, IKZF1, IL6R, IRF8) while apoptotic genes were down-regulated (CASP3 and CASP8). This evidence concerns the gene IKZF1 and rheumatoid arthritis.