In uveal melanoma and OSCC, the overexpression of FTH1P3 decreased miR-224-5p expression and promoted the expression of Frizzled 5, which was the direct target genes of miR-224-5p; in uveal melanoma, the expression of Ras-Related C3 Botulinum Toxin Substate 1 (Rac1) is also affected by the influence of FTH1P3/miR-224-5p [84,85]. This evidence concerns the gene RAC1 and uveal melanoma.