Finally, Yang et al. have suggested a possible impact of FTH1P3 on the expression of SP1 and Nuclear Factor Kappa-light-chain-enhancer of activated B cell (NF-κB) (p65) in esophageal squamous cell carcinoma cells [86], although the evidence supporting this suggestion is still poorly consolidated. This evidence concerns the gene FTH1P3 and esophageal squamous cell carcinoma.