According to our data, although the percentage of macrophages (F4/80+CD11b+) infiltrating the tumor tissues was no different between FBXW7f/f and Lysm+FBXW7f/f mice, a higher percentage of CD206+ subset in macrophages was observed in the FBXW7-knockout group (Figure 2C, 2D). The gene discussed is ITGAM; the disease is neoplasm.