EGR1 and hepatocellular carcinoma: First at the transcriptional level, TTP expression could be directly induced by transcription factor ELK‐1 and EGR‐1 through binding the TTP promoter38; Methylation of a specific single CpG site (−500 bp) within the TTP promoter region could suppress TTP transcription in HCC cell and blockade of DNA methylation in this CpG site could increase TTP expression.11