LAPTM5 (lysosomal‐associated protein transmembrane 5) is a membrane protein that can inhibit the expression of T‐cell receptor (TCR) and play a positive role in migration and invasion of ovarian cancer cell but play a negative regulator of T‐cell or B‐cell receptor downstream signalling.47, 48, 49. This evidence concerns the gene LAPTM5 and ovarian carcinoma.