ASIC3 and peripheral neuropathy: The role of ASIC3 in neuropathic pain has been further evaluated using the cisplatin model of chemotherapy-induced peripheral neuropathy, which causes hyperalgesia and allodynia in rodents [82], increased expression of ASIC3 being observed in DRG neurones innervating the gastrocnemius muscle, alongside mechanical hyperalgesia, which was ameliorated by the ASIC inhibitor amiloride [83].