BRCA1 and ovarian cancer: For these patients, the cumulative risk for ovarian cancer from 25 to 50 years is 6%, 11%, and 2% respectively, which combined with the average mortality, which is substantially lower than in BRCA1/2-associated or sporadic ovarian cancer, indicate a risk of dying from a premenopausal ovarian cancer to be 1%, 2%, and 0%, respectively.