ERBB2 and cancer: To further evaluate the anti-cancer activity of the compounds, we assayed the growth inhibitory activity of resveratrol, since it is the most abundant component of TriCurin, on the oestrogen receptor (ER)-negative, Her2-overexpressing human breast cancer line MDA-MB-453; the IC50 value was: 1.91 μg/mL (8.32 μM) (Fig. 4a).