USP24 knockdown (KD) in H1299 lung cancer cells and U2OS bone cancer cells decreased levels of the BRD-containing proteins including BRG1, BRD7, BRD1, BRD3, GCN5, PCAF, and TIF1α (Fig. 1A and Suppl.Fig. 1B). This evidence concerns the gene SMARCA4 and bone neoplasm.