At univariate Cox regression analysis (described in Table 2), variables associated with in-hospital mortality were: CVD other than hypertension (P < 0.001), presence of dyspnea at hospital admission (P < 0.001), higher Brixia and CALL scores (P = 0.02 and 0.005, respectively), higher levels of gamma glutamyl transferase (P = 0.001), a blood sodium level > 145 mmol/L (P = 0.003), lymphocyte count < 1000 cells/μL (P = 0.03), higher levels of D-dimer (P = 0.004) and serum Interleukin-6 (P < 0.001), C reactive protein > 50 mg/L (P = 0.02), and corticosteroid therapy (P < 0.008). This evidence concerns the gene CRP and hypertensive disorder.