Compared with normal samples, tumor samples had significantly increased fractions of CD8 + T (1.46–1.80%, P = 0.006) and NK cells (0.80–1.37%, P = 3.65e-13), and decreased fractions of neutrophils (4.28–3.07%, P = 5.44e-6) (Fig. 2f). The gene discussed is CD8A; the disease is neoplasm.