CD4 and neoplasm: In addition, the percentages of CD8+IFNγ+, CD4+IFNγ+, CD4+IL-4+, or CD4+IL-17+ T cells in the bronchial dLNs were comparable between KP and KP7 mice, whereas the numbers of CD8+IFNγ+ T cells were significantly decreased and the numbers of CD4+IFNγ+, CD4+IL-4+, or CD4+IL-17+ T cells were also decreased in bronchial dLNs from KP7 mice compared to KP mice (Fig. 4b, and Supplementary Fig. 6b, c), suggesting that CCL7 deficiency impairs CD8+ T cell expansion in the bronchial dLNs after tumor induction in the KP mouse model.