Other frequently recurring fused kinases are ALK (found in 18 cell lines) and ROS1 (in 6 cell lines), both well known as cancer drivers in lung adenocarcinoma (EML4-ALK fusion) and non-small cell lung cancer (ROS1 rearrangements), for which different inhibitor drugs have been developed34,35. Here, ALK is linked to non-small cell lung carcinoma.