Finally, we found that the PBMCs obtained from ZD55-IL-24-treated mice (mice without receiving tumor inoculation) could specifically kill ZD55-IL-24-treated B16 cells in vitro (Fig. 6M), indicating that the anti-viral specific immune response induced by ZD55-IL-24 could act specifically against the tumor cells infected with ZD55-IL-24, indirectly demonstrating that ZD55-IL-24 viral infection could result in the presentation of “nonself” viral epitopes on the surface of tumor cells. Here, IL24 is linked to neoplasm.