IL24 and neoplasm: Through analysis of the above down-regulated and up-regulated cytokines, we noticed that five down-regulated cytokines had a function of suppressing antitumor immunity (Fig. 3A), and 83 up-regulated cytokines had a function of promoting antitumor immunity (Fig. 3B), hinting that ZD55-IL-24 probably inhibited tumor growth in B16-bearing immunocompetent mouse model through inducing antitumor immunity.