IL24 and melanoma: Indeed, although ZD55-IL-24 can also induce innate antitumor immunity in local tumors (Fig. 8I–P), the antitumor immunity pathway in fact contributes little to the overall anti-melanoma efficacy of ZD55-IL-24 in A375-bearing immunodeficient mouse model (Figs. 1A–D, 3K–M).