The developed final model contained the effects of CrCL and infection sites (pneumonia [CREDIBLE-CR and APEKS-NP studies], BSI/sepsis, cUTI [CREDIBLE-CR study], or cUTI/AUP [APEKS-cUTI study]) on CL, body weight on the volume of distribution in the central and peripheral compartments (V1 and V2, respectively), albumin concentration (ALB), and any of the infection sites on V1. The gene discussed is ALB; the disease is pneumonia.