Compared to the pCMV6-A-GFP group, the xenograft tumor weight was significantly decreased in the pCMV6-A-GFP-MEG3 group (0.86 ± 0.108 g vs 0.37 ± 0.053 g, P = 0.000175 < 0.01). This evidence concerns the gene MEG3 and neoplasm.