Compared to the pCMV6-A-GFP group, the appearance time of xenograft tumor was increased in the pCMV6-A-GFP-MEG3 group (14.33 ± 1.75 days vs 7.83 ± 1.17 days, P = 0.00001124 < 0.01). The gene discussed is MEG3; the disease is neoplasm.