MiR-192-5p, a liver-abundant miRNA, is functionally important in suppressing the stemness and malignancy features of HCC cells, and its genetic silencing frequently occurs in multiple groups of CSC+ HCCs, i.e., EpCAM+, CD90+, CD133+, CD44+, and CD24+ HCCs [23]. This evidence concerns the gene PROM1 and hepatocellular carcinoma.