CXCR3 and cardiovascular disorder: After releasing from leukocytes and endothelial cells, CXCL10 binds to its receptor (G protein – coupled receptor; CXCR3), and leads to a range of inflammatory and immune responses (meaning the regulation of leukocyte and lymphocyte traffic to the damaged tissue); key factors in cardiovascular diseases (CVD) such as atherosclerosis, myocardial infarction [46–48], and cardiac remodeling [49].