ADIPOQ and hepatocellular carcinoma: As for AdipoQ, Cai et al. [42] found that the AdipoQ rs1501299 was associated with the increased susceptibility to HCC, and the additive model showed that the GT and GG genotypes were significantly associated with an increased risk in HCC (GT vs TT: OR = 2.83, 95% CI (1.36, 5.89), P = 0.006; GG vs TT: OR = 4.52, 95% CI (2.25, 9.11), P = 0.001).