TNF and tuberculosis: When comparing the TB incidence rates in TNF-α inhibitors users in the SABIO registry, incidence was 1387 per 100,000 person-years, which is approximately 10-fold that of the British (BSRBR), French (RATIO) and Spanish (BIOBADASER) registries where the TB incidence ranges from 106 to 172 per 100,000 person-years [22, 24].