The highest frequency was observed in acute lymphoblastic leukemia (ALL) (total: 19%; mut+del: 6%; mut only: 8%; del only: 5%) and acute myeloid leukemia (AML) (total: 13%; mut+del: 5%; mut only: 7%; del only: 1%), whereas TP53 alterations occurred less frequently in chronic lymphocytic leukemia (CLL) (total: 8%) and myelodysplastic syndromes (MDS) (total: 7%) [103]. The gene discussed is TP53; the disease is acute myeloid leukemia.