DOCK1 is implicated in neural growth and is a member of the KEGG pathway term “Regulation of actin cytoskeleton” and NPS in “positive regulation of synaptic transmission, glutamatergic” (GO:0051966) and “regulation of synaptic transmission, GABAergic” (GO:0032228), among others, all processes that are linked to ALS (see Section 1.1) [113,148]. The gene discussed is DOCK1; the disease is amyotrophic lateral sclerosis.