Semiquantitative scoring analysis of S100A1 in paraffin-embedded sections of 18 conjunctival nevi, 16 conjunctival melanomas, and 20 uveal melanomas found that S100A1 was more frequently expressed in conjunctival melanoma (71.4% positive cells) and uveal melanoma (88.5%) than in conjunctival nevi (30.6%) [150]. Here, S100A1 is linked to malignant conjunctival melanoma.