NOS2 and colitis: Given the well-demonstrated anti-inflammatory and antioxidant effects of the majority of the molecules present in Klamath algae, as phycocyanins that selectively inhibit key enzymes in inflammatory disease as COX-2, and iNOS, and the high concentration of these components in AphaMax®, the aim of our study was to investigate the possible protective potential of this extract in an animal model of IBD, the 2,4-dinitrofluorobenzenesulfonic acid (DNBS) -induced rat colitis.