NPM1 and chronic myelomonocytic leukemia: By targeted gene sequencing on BM samples from 35 Korean patients with CMML, Hwang et al. recently found slightly different mutational profiles, with lower frequency of TET2 mutations (25.7%) and higher frequencies of DNMT3A (17.1%), NRAS (31.4%) and NPM1 (11.4%) mutations compared with those documented in previous studies from Caucasian CMML cases as summarized in Table 4 [80].