The expression levels of Tfr1 are increased in several cancer types, including glioma, lung, colorectal, pancreatic, breast, bladder, and ovarian cancers, but also hematological malignancies such as non-Hodgkin’s lymphoma and chronic lymphoid leukemia [45,53,65,69,80,85,87,97,109,129]. Here, TFRC is linked to cancer.